Ep. 2: Predict, Treat, Monitor: The Quest for Smarter Immunotherapy Decisions | 23 mins → Ep. 2: Predict, Treat, Monitor: The Quest for Smarter Immunotherapy Decisions

Ep. 2: Predict, Treat, Monitor: The Quest for Smarter Immunotherapy Decisions | 23 mins 1

In our second episode of our special vodcast series, Redefining Immunotherapy: Lessons from Melanoma, our experts tackle one of the biggest challenges in modern oncology: how do we make smarter immunotherapy decisions for individual patients?

The panel explores the real-world factors that shape treatment selection in advanced melanoma; from tumour burden, brain and liver metastases, and BRAF mutation status, to patient age, fitness and comorbidities. They unpack the evolving role of combination immunotherapy, including PD-1 monotherapy, ipilimumab/nivolumab and newer LAG-3 combinations, while weighing the balance between efficacy and toxicity.

The discussion also dives into the promise and limitations of biomarkers such as PD-L1, tumour mutational burden (TMB), interferon gamma signatures and MSI-high status, and examines why predicting response to immunotherapy remains one of the field’s greatest challenges.

Blending practical clinical insight with emerging research, this episode offers a thoughtful and highly relevant discussion on personalising immunotherapy in the pursuit of more durable outcomes, and ultimately, cure.

This special edition vodcast from “Melanoma Insights for Professionals” is suitable for Medical Oncologists, Oncology Nurses and other health professionals.

If you missed our first episode, take a look here or search “Melanoma Insights” in Spotify or your favourite podcast app.

SPEAKERS
Prof Georgina Long AO
Medical Oncologist
Melanoma Institute Australia and The University of Sydney
Declaration of Interest

A/Prof Alexander Menzies
Medical Oncologist
Melanoma Institute Australia and The University of Sydney
Declaration of Interest

A/Prof Ines Silva
Medical Oncologist
Melanoma Institute Australia
Declaration of Interest

A/Prof Matteo Carlino
Medical Oncologist
Melanoma Institute Australia and The University of Sydney
Declaration of Interest

Please note that this presentation was accurate at the time of recording (April 2026) but may not reflect the rapidly evolving treatment landscape and approvals in Australia.

This special vodcast is an initiative of Melanoma Institute Australia and made possible by an unrestricted educational grant from Bristol Myers Squibb.
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  Ep. 2: Predict, Treat, Monitor: The Quest for Smarter Immunotherapy Decisions | 23 mins
  23 min

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Question 1: Rate the degree to which the program learning outcomes were met:

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Question 1: Rate the degree to which the program learning outcomes were met

Not met Partially met Entirely met

Question 2: Please rate to what degree this CPD activity met your expectation about:

Not met Partially met Entirely met

Question 3: Would you likely recommend this CPD activity to a colleague?

Question 4: Would you likely change anything in your practice as a result of this CPD activity?

Question 1: Rate the degree to which the program learning outcomes were met

Not met Partially met Entirely met

Not relevant Somewhat relevant Highly relevant

Question 1: Rate the degree to which the program learning outcomes were met:

Not met Partially met Entirely met

Question 2: Rate the degree to which the program learning outcomes were met:

Not met Partially met Entirely met

Question 1: Rate the degree to which the program learning outcomes were met

Not met Partially met Entirely met

QUESTION 2: Please rate to what degree this CPD activity met your expectation about:

Not met Partially met Entirely met

Not relevant Partially relevant Entirely relevant

Question 1: Rate the degree to which the program learning outcomes were met

Not met Partially met Entirely met

Question 2: Please rate to what degree this CPD activity met your expectation about:

Not met Partially met Entirely met

Question 3: Would you likely recommend this CPD activity to a colleague? Yes/No Why?

Question 4: Would you likely change anything in your practice as a result of this CPD activity? Yes/No Why?

Question 1: Rate the degree to which the program learning outcomes were met

Not met Partially met Entirely met

Not relevant Somewhat relevant Highly relevant

Question 1: Rate the degree to which the program learning outcomes were met

Not met Partially met Entirely met

Question 1: Rate the degree to which the program learning outcomes were met

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Question 1: Rate the degree to which the program learning outcomes were met:

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Question 1: Rate the degree to which the program learning outcomes were met

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Ep. 2: Predict, Treat, Monitor: The Quest for Smarter Immunotherapy Decisions | 23 mins 1

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